Food Drug Interaction

Common Medication Which Cant Take With Alcohol

• Acetaminophen

Combination of acetaminophen and alcohol will lead an synergistic effect that harm our stomach and lead to ulceration bleeding. In addition , combination will lead to a toxic compound which lead to liver toxicity or reduce liver function.

Brand name Of This Medication : Panadol , Tylenol

• Benzodiazepines Deriavtive Drug

Combination will lead to excessive concentration in blood. Toxicity will happen and most serious effect is respiratory depression might occur which might lead to death.

• Chorpropamide

Concurrent with alcohol will lead to inhibition of liver enzyme. It might delay the clearance of chlopropamide and lead to hypoglycemia and hypotension

Brand name Of This Medication : Diabenase

• Cimetidine

Cimetidine is a Liver enzyme inhibitor. Concurrent with alcohol will lead to delay of the alcohol in body. It will lead to get drunk easily (than usual) and hanging effect of the alcohol.



Brand name Of This Medication : Tagamat

• Warfarin

Warfarin is an anticoagulant agent which use in as prevention of drug clotting.Concurrent with alcohol will lead to synergistic effect and lead to uncontrolled bleeding. Death will occur if uncontrolled bleeding in brain , stomach.

Brand name Of This Medication : Marevan , Coumadin

• Furesemide

It act as diuretic which use for patient present with edema or high blood pressure. Since alcohol also diuretic. Synergistic effect will happen and might lead to hypotension since loss of excessive fluid in body.

Brand name Of This Medication : Lasix

• Amitriptyline

It is an anti depressant drug. When take conccurent with alcohol, alcohol will delay the clearence of the drug and excessive absorption will lead high concentration in our body. Overdosage of this medication are hallucination , tremor , loss of appetie and nausea and vomitting.

Brand name Of This Medication : Tryptanol , Laroxyl , Saroten

Food Drug Interacion

Common Drugs Which Cant Take with Cola / Acidic Drink

Cola or other acidic drink play a role in drug absorption. pH of this beverage are 2.5-4.2. When take with medication , the acidic condition will make the drug easy dissolved or the other

• Aspirin

This medication usually use as analgesic, antipyretic or anti platelet. Aspirin needs to dissolve in alkaline condition. If Cola or acidic drinks present in stomach, the acidic environment will be created and might lead some difficulty in dissolve the aspirin in the stomach. It might suppress the effect of aspirin

Brand name for this medication : Aspirin , Gliperin

• Iodochlorhydroxyquin compunds

The iodochlorhydroxyquin compound product mainly use for an antidiarrheal but now used mainly as an antiseptic When acidic drink take with this compound , over absorption's might occur and concentration might be occur. This will lead some side effect of the drug such as nausea , vomiting and acute liver failure. Avoid take this medication with acidic beverage.

• Theophylline

This medication usually use to treat COPD or asthmatic patient. When theophylline take with acidic drink , research shown that acidic drink will increase the
lead to side effect of theophylline. Side effects are acute depression and might lead to severe depression or insomnia.

Food Drug Interaction

Common Medications Which Cant Take with Caffeine

Usually all type of teas available in the market contain caffeine in their ingredients. It uses as energy booster in our body. Anyhow , if overdose of caffeine , headache , palpitaion , tachycardia and insomnia might occur.

• Cimetidine

It classified as H2 antagonist which use to inhibit the secretion acid in our stomach. Usually it use to treat of heart burn , mild to moderate GERD (Gastroesophageal Reflux Disease). If this medication take concurrently with caffeine. sign and symptom overdose of this drug might be happen. It is due cimetidine is a liver enzyme inhibitors. It will delay the drug clearence time in our body. Then less caffeine will be excreted out through our body. headache , palpitation , tachycardia and insomnia might occur. In serious condition , epilepsy might occur and very dangerous since it can lead to death

Brand name for this medication : Tagamat , Tamedin , Defense , Ciyanlin

• Diazepam

It is known to use in treating anxiety or acute epilepsy. When it take concurrently with caffeine , the caffeine might inhibit diazepam efficacy and lead to no effect if concentrated caffeine present in our body. It is dangerous for patient who have history of anxiety and epilepsy.

Brand name for this medication : Valium , Vancolin , Dupin , Horizon

• Theophylline

This medication is used in coronary disease such as asthma or COPD patient. Side effect of the theophylline and caffeine are the same. Example such as nausea, diarrhea, increase in heart rate, arrhythmias, and CNS excitation (headaches, insomnia, irritability, dizziness and lightheadedness) . If take caffeine concurrenly then synerhistic effect might occur and toxicity might be worsen.

Brand name for this medication :Theovent , Neulin , Uni-Dur , Uniphylin

• Chlopromazine

This medication is indicated as anti-psychotic drug. When take concurrently with caffeine . chelation might occur and absorption in the intestine might decreased. Lower efficacy might be occured and the disease cant be controlled properly.

Brand name for this medication : Wintermin , Morefine , Sintomin

Common Medication Which Cant Take With Green Tea

• Mineral Ferrous

Mineral Ferrous is indicated for anemia patient. In Green tea, it contains tannic acid which will lead to chelation when take concurrently with ion ferrous. It will lead to low absorption in our body and affect the efficacy of the drug. It is recommend that no green tea when take the hematinic supplement for anemia.

Food - Drug Interaction

Common Drug Which Cant Take With Milk or Dairy Product

• Tetracyclin & Achromycin

This medication are antibiotic which use in killing harmful bacteria and prevent infection in our body to get worsening. Since milk or dairy product contain high level of calcium , chelation will happen when this medication take together with milk or dairy product. Chelation will make the molecule of this drug become bigger and lower the body absorption for this medication. This will lead to less medication pass through our body. The effectiveness of this antibiotic will be decreasing. Resistance of antibitoc might occur if the antibiotic is not much enough to kill the bacteria.

Brand name of this medication : Vibramycin , Minocin

• Vitamin A
  

Vitamin A (tigason) is a drug which is used in treating psoriasis. Anyhow , if this take with milk , it will lead to inactivation of the liver metabolism enzyme and lead to toxicity of this medication

Brand name of this medication : A.D.E , Almain , C0al

• Cyclosporin

It is an immunosuppresant which use to inhibit and prevention rejection in patient who undergoing organs transplant. Mixing with milk will lead to excessive absorption. This will inhibit liver enzyme and lead to liver failure.

• Bisacodyl

It is an laxatives which use in patient with constipation. This medication is coated in tablet to be dissolved in the intestine in order to give a laxative effect. Anyway, when milk is combined with bisacodyl , the stomach acidity will be neutralized by the milk or the dairy product. the coating bisacodyl in the tablet will dissolve in a stomach due the changes acidity of the environment. No effect will be observed for bisacodyl if it dissolve in the stomach instead of the small intestine.

Brand name of this medication : Dulcolax , Bidyl , Tonlaxan , Licodyl

Storage of the Medication

Storage of the medication is important since it will directly will affect the effectiveness of the medication. Medication can be useless if you store in wrong place and wrong temperature.

Example is that Insulin will completely loss it effect as anti diabetic agent if we kept in a hot temperature. It is due to the molecule will break into parts which is useless to our body as lowering our sugar in our body.

Here some tips to Keep common medication

• Avoid expose direct to the sunlight. Keep in a dry place with room temperature
• Avoid keep the medication in shower. Moisture in bath room might make the medication spoiled.
• Keep in a place where children hard to reach.
• Medication which only use application only need to separate storage with the medication for inner usage
• Avoid store the medication in different medication container. Better keep in original container to prevent contamination or confusion of the medication
• Medication which need store in low temperature (refrigerator) only allowed put in the cooler. Need to avoid putting it at the freezer.
• Medication which store in the fridge need to be separated from the food to prevent toxicity
• Expired date of the medication need to be observed every time take any medication. (Usually the oral medication can store from 2 years from the manufacturing date)
• Drug which need to be exposed or unused medication and expired drug can flush into toilet bowl. The safest way is return it to the pharmacy department where professional pharmacist will help you for the unused medication.
• Most importantly please follow the storage instruction according the medication leaflets
  

Drug & Medication

Drug and medication is related to us everyday . It is useful when we are sick or maintain our health. Do you know what is drug and medication ? Do you know how to store the medication to ensure it is effective as ever when you use it next time?

As layman , their mind only know medication when they sick or feel discomfort. Dose they ever think of is the medication usable? Is medication expired? Is the medication store in proper place? When is the best time to take the medication? Before food / After food? I can 100% guarantee all patient wont bother all this. As long they think they take medication , the sick will resolve. It is wrong.

Do you can move a car with water? same as do you think an expired drug will help you? Answer sure is no! Do a drug will help you if you take some food which may decrease the effectiveness of the drug? Sure is not!!

In addition , toxicity might occur if you take some medication with food which might synergistic of the effect of the drug... That why a correct and practical knowledge need to be known in order to use our drug and medication effectively.